HORDB

ID: hor005667
Uniprot ID: Q76CL2
Protein name: Peptide YY
Gene name: pyy
Organism: Anguilla japonica (Japanese eel)
Family: NPY family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Anguilla (genus), Anguillidae (family), Anguilliformes (order), Elopomorpha, Elopocephala, Elopocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: YPPKPENPGEDASPEEQAKYYTALRHYINLITRQRY
Length: 36(29-64)
Propeptide: MAVVLKPWTVLVALVLCLLVCLGTFVDAYPPKPENPGEDASPEEQAKYYTALRHYINLITRQRYGKRSSPEGVMSELLFGDNSEHNQRSRYDDSYMW
Signal peptide: MAVVLKPWTVLVALVLCLLVCLGTFVDA
Modification: T36 Tyrosine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005667_AF2.pdb

hor005667_ESM.pdb

Mass:	493421	Formula:	C194H291N53O59
Absent amino acids:	CFMVW	Common amino acids:	PY
pI:	7.52	Basic residues:	6
Polar residues:	11	Hydrophobic residues:	7
Hydrophobicity:	-141.94	Boman Index:	-10403
Half-Life:	2.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	2 min	Aliphatic Index	51.67
Instability Index:	8235.83	Extinction Coefficient cystines:	7450
Absorbance 280nm:	212.86